sogood wrote:Ant. wrote:My body wants calcium; every athletes body wants more calcium compared to the average couch potato. I'm giving it an alternate source so it doesn't need to pluck it from my bones
It's biologically plausible, so it satisfies me.
Well, I actually don't think this makes sense given what we know of the general principles by which the body operates.
Through negative feedback and other mechanisms, overdosing may induce a temporary benefit. But over time, it'll induce down regulation in the various systems to normalize the effective absorption and end effect At the end of the day, if the osteoclast and osteoblasts aren't getting the appropriate signals induced by stress and strain, then there will be resorption. We know this as bone remodelling to physical forces is a well documented. And even with impact training, there's an upper limit as to how far the bone would respond.
At the end of the day, it's a probability thing as shown by the percentage of study subjects who were noted to have the problem. So fingers crossed.
I don't think that stress and strain are the only signals that bring about positive bone remodelling, however I don't doubt that they're the most important. From memory, thyroxine, growth hormone also signal bone growth (which requires calcium which brings out parathyroid hormone) and maybe testosterone (but that one is a pure guess based on it's other anabolic activities), and they're all expressed after (and maybe during?) exercise. I know I'm not telling you anything new here
If there's more calcium available (not meaning plasma calcium obviously, meaning more ingested and more stored in the bones), then there won't be that net negative calcium deficit when everything is said and done.
What I should really search up on (ie, email a professor on the topic
), how beneficial is the effect of bone density of regularly consuming more than the RDI levels of calcium versus the 1000mg per day... how strong is the dose-response relationship, and can that be modified/increased some way?
Had never considered downregulation though
May well come into effect, but even the type II people still benefit from exogenous insulin.